Champagne has a unique, light and bubbly texture that crackles
and fizzes on application. This patented delivery system
instantly cools the skin on contact and penetrates ingredients
deep into the lower dermal layers. Because Champagne delivers
the Tri-Peptide technology at such a rapid rate, the skin and
cell rejuvenation process begins immediately. The instant
cooling sensation, followed by a slight feeling of warmth,
signals
that the patented technology is working to help firm, tone, and
lift target areas of the body.
You
will love the instant stimulating sensation of Champagne and
will be satisfied with the long-term results of softer, younger
looking skin.
Peptides play a vital role
in the skin's healing process. These protein
molecules, found
naturally in the body, send out signals when damaged skin is in
need of repair.
Champagne's patented ingredients
target both the upper and lower levels of the skin, helping to
reduce wrinkles, stretch marks and cellulite.
Acetyl Hexapeptide-3
Clinically proven to reduce skin irregularities by relaxing
tense muscles, while simultaneously improving collagen and
elastin production.
Review Clinical Study
Palmitoyl Oligopeptide
Clinically prove to strengthen and repair the skin by
stimulating cellular activity, plus enhancing moisture retention
and reducing dryness.
Review Clinical Study
Palmitoyl Tetrapeptide-3
Clinically proven to control the body's production of cytokines,
the chemical messengers that trigger inflammation and premature
aging.
Review Clinical Study
After
having my son, Jordan, I was left with horrifying stretch marks.
Still being young, I wanted to wear bikinis and hip clothes. My
stretch marks looked like I’d been attacked by a bear. They were
dark, deep, and wide. My husband knew how embarrassed and
self-conscious I was, so he bought me Champagne. I was
skeptical, because I’ve tried so many products that didn’t work.
When I tried it for the first time, I couldn’t believe the cool,
refreshing feeling. It reminded me of Pop Rocks as it crackled
on my skin. Champagne is the neatest product I’ve ever tried.
Now, my skin is tighter and my
stretch marks have lightened a ton, as you can see in my
pictures. Champagne is a stretch mark miracle! I never thought
I’d wear a bikini again.
Thanks.
Ashley
McKinney, TX
About two months before my wedding, my fiancé told me
I needed a passport for our honeymoon, but he wouldn’t
tell me where we were going. He wanted to surprise me
with a trip to Tahiti, but knew I’d never go because I
hate being seen in a bikini. After bugging him to death,
he finally told me. Panicked, I knew I had to get my winter body ready
for summer – and fast. I was really nervous about the
cellulite on my thighs. I tried Champagne, because my
friend swears by it. My thighs look awesome. They are smoother and firmer.
I’m so thrilled with the results. Champagne saved my
honeymoon from cellulite. I was definitely ready to get
romantic in Tahiti! Thanks!
Acetyl Hexapeptide-3 is
used in formulas as a wrinkle preventative as well as a wrinkle
reducer as an alternative to injections.
Acetyl Hexapeptide-3 is a
mimic of the N-terminal end of SNAP-25, one of three proteins
(known as the SNARE complex) that are essential for
neurotransmitter release at the synapsis, which is the chemical
signal for a muscle to contract.
As a wrinkle reducer,
studies have shown that Acetyl Hexapeptide-3 at a 10%
concentration was able to significantly decrease the depth of
wrinkles after 30 days of treatment. The mechanism by which
Acetyl Hexapeptide-3 is able to accomplish this is related to
the ways in which Acetyl Hexapeptide-3 is able to assist wrinkle
prevention.
Acetyl Hexapeptide-3
performs this activity in two distinct ways:
The first way Acetyl
Hexapeptide-3 acts as a wrinkle preventative is by competing
with SNAP-25 for a position in the SNARE complex. This
destabilizes the SNARE complex, preventing the vesicle from
releasing neurotransmitters efficiently, and therefore
attenuating muscle contraction. This causes a reduction in
facial muscle contraction, which is believed to help prevent the
long-term formation of lines and wrinkles.
The second way that Acetyl
Hexapeptide-3 acts as a wrinkle preventative is by reducing the
release of catecholamines (the overproduction of which is known
to induce the formation of wrinkles and fine lines in the skin),
specifically adrenaline and noradrenaline. Acetyl Hexapeptide-3
is non-toxic and well tolerated by the skin.
Like Palmitoyl
Pentapeptide-3, Biopeptide-CL is a synthetic protein that is a
fragment of collagen combined with palmitic acid to make it more
lipophillic, to improve its stability and to enhance its
affinity towards human skin. As with Palmitoyl Pentapeptide-3,
one could look at Biopeptide-CL as a man-made precursor to
collagen.
Biopeptide-CL was developed
through research to identify a substance that would behave
similarly to retinoic acid but without its drawbacks, especially
in regards to synthesizing collagen.
The reported results are as
follows:
In vitro:
Increases collagen production by the fibroblasts by as much as
350%.
Increases hyaluronic acid production by the fibroblasts by as
much as 146%.
In vivo:
The following statistics were gathered using image analysis of
volunteers who used crèmes containing a 3% concentration of
Biopeptide-CL for 28 days.
Surface roughness --- Reduced 17%
Mean depth of wrinkles --- Reduced 23%
Depth of main wrinkle --- Reduced 39%
Skin thickness --- Increased 4%
The increase in skin
thickness was considered especially notable and contrasts with
the 6% reduction of the skin thickness that occurs after 10
years of aging. The study concludes to state that Biopeptide-CL
is a potent active cosmetic ingredient without the adverse
effects (including irritation, dehydration or long-term toxicity
and instability) characteristic of retinoids.
Palmitoyl Tetrapeptide-3 is
a synthetic peptide that is a fragment of immunoglobulin G that
has been combined with palmitic acid to make it more lipophillic
and thus enhance its affinity towards human skin. Palmitoyl
Tetrapeptide-3 was discovered through research to learn how to
suppress the body's production of interleukins, particularly
IL6, since these are the chemical messengers that trigger the
body's acute inflammatory response.
Inflammation is a function
of immunity and is a protective response to injury or
destruction of tissue. This is the body's way of walling off the
injurious agent and the injured tissue. Under normal
circumstances, very little IL6 is secreted and its secretion is
strictly controlled. However, as we age this regulation system
develops defects, and significant levels of IL6 appear in the
plasma even when there is no inflammatory stimulus. This results
in high levels of inflammatory proteins in the tissues and a
loss of healing potential. This process has been linked with
breast cancer, osteoporosis, anemia, autoimmunity and slower
tissue regeneration.
The hormone DHEA is
directly responsible for maintaining the regulation of the
production of IL6. This has even been demonstrated in the skin:
when DHEA is present in sufficient amounts it is converted into
a steroid hormone, androstenediol, which is directly responsible
for maintain IL6 production and for maintaining local
homeostasis of cytokine and interleukin production. As we age,
DHEA is reduced and this directly leads to cytokine deregulation
and the over-production of some interleukins and the
under-production of others. As mentioned above, IL6 production
is increased with negative consequences. Since UV radiation can
increase IL6 production by five times, this process can
significantly impact the skin.
The researchers' goal thus
became to find a peptide that would mimic the effects of DHEA
without DHEA's potential for being converted into estrogen,
since estrogen is a hormone that is not licensed for cosmetic
purposes. Specifically they wanted to find a peptide that would
target IL6 and inhibit its production. The results:
At concentrations from
10 ppm, Palmitoyl Tetrapeptide-3 induces a marked reduction
in the secretion of the cytokine IL6. This reduction is
progressive and depends on the concentration of the peptide:
baseline secretion may be inhibited by up to 40%.
Palmitoyl
Tetrapeptide-3 reduced levels of IL6 after cells were
exposed to UV radiation by up to 86% even though IL6 had
been increased by about 20 fold by the UV.
These results show that
Palmitoyl Tetrapeptide-3 is able to affect baseline levels of
IL6 as well as modulate the effects of UV-stimulated
over-production of IL6. IL6 is marketed by Sederma as a molecule
that can restore cytokine equilibrium, which characterizes
youthful skin. 1-800 Patches has chosen to use Palmitoyl
Tetrapeptide-3as a synergistic support ingredient to create a
more optimum environment for other active ingredients to help
restore youthful skin appearance.
tm
the skin on contact and penetrates ingredients
deep into the lower dermal layers. Because Champagne delivers
the Tri-Peptide technology at such a rapid rate, the skin and
cell rejuvenation process begins immediately. The instant
cooling sensation, followed by a slight feeling of warmth,
signals
that the patented technology is working to help firm, tone, and
lift target areas of the body. 
After
having my son, Jordan, I was left with horrifying stretch marks.
Still being young, I wanted to wear bikinis and hip clothes. My
stretch marks looked like I’d been attacked by a bear. They were
dark, deep, and wide. My husband knew how embarrassed and
self-conscious I was, so he bought me Champagne. I was
skeptical, because I’ve tried so many products that didn’t work.
When I tried it for the first time, I couldn’t believe the cool,
refreshing feeling. It reminded me of Pop Rocks as it crackled
on my skin. Champagne is the neatest product I’ve ever tried.
